Integrated Graduate and Continuing Education in Protein Chromatography for Bioprocess Development and Scale-up


  • Giorgio Carta University of Virginia
  • Alois Jungbauer University of Natural Resources and Life Sciences (BOKU)


We describe an intensive course that integrates graduate and continuing education focused on the development and scale-up of chromatography processes used for the recovery and purification of proteins with special emphasis on biotherapeutics. The course includes lectures, laboratories, teamwork, and a design exercise and offers a complete view of the development and scale-up of a biochromatography, from biomolecular properties, to initial laboratory testing, to final design.

Author Biographies

Giorgio Carta, University of Virginia

Giorgio Carta received his Ph.D. in chemical engineering from the University of Delaware in 1984. Since then he has been a professor in the Department of Chemical Engineering at the University of Virginia, Charlottesville (USA), where his research focuses on transport phenomena and bioseparations. He regularly organizes professional courses on various aspects of bioseparations, including a course together with Alois Jungbauer on protein chromatography development and scale-up.

Alois Jungbauer, University of Natural Resources and Life Sciences (BOKU)

Alois Jungbauer is the head of protein technology and downstream processing at the Department of Biotechnology of the University of Natural Resources and Life Sciences in Vienna (Austria). For more than 20 years, Professor Jungbauer has worked in biochemical engineering, with a focus on biosparation, where he has published widely and holds 15 patents. For more than 10 years, he has organized a biennial professional course in protein chromatography focused on mass transfer, dispersion, and scale-up.