Twenty-one selected cotton (Gossypium hirsutum L.) cultivars, representing a range of reaction types to the Fusarium wilt/root-knot nematode disease complex, were evaluated for response to the disease complex and to Fusarium oxysporum f. sp. vasinfectum and Meloidogyne incognita in field microplots infested with both pathogens. Resistance to the disease complex was based on plant mortality, whereas resistance to F oxysoprum f. sp.. vasinfectum was based on vascular browning. Resistance to M. incognita was based on population densities of eggs and juveniles per 500 cm of soil at crop maturity. In general, cultivars reacted to the disease complex as expected and those reported to be resistant to the disease complex were also more resistant to F. oxysporum f. sp. vasinfectum than those cultivars reported as susceptible. In contrast, there was little difference among cotton cultivars in reaction to M. incognita. Only 'Auburn 634' was highly resistant to the nematode. In fields infested w